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Symbol
Name
ID

Brca1
breast cancer 1, early onset
MGI:104537

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Leukopenia	Lymphadenopathy	Hepatosplenomegaly	Peritoneal abscess	Recurrent urinary tract infections
Disease(s) Associated with BRCA1	Leukopenia	Lymphadenopathy	Hepatosplenomegaly	Peritoneal abscess	Recurrent urinary tract infections
Fanconi anemia
pancreatic cancer

Mouse Phenotypes		decreased T cell proliferation	decreased thymocyte number	increased double-negative T cell number	decreased double-positive T cell number	abnormal T cell number	decreased single-positive T cell number	abnormal immune system organ morphology	dermatitis
Availability	Mouse Genotype	decreased T cell proliferation	decreased thymocyte number	increased double-negative T cell number	decreased double-positive T cell number	abnormal T cell number	decreased single-positive T cell number	abnormal immune system organ morphology	dermatitis
	Brca1^tm5.1Cxd/Brca1^tm5.1Cxd
	Brca1^tm2Mak/Brca1^tm2Mak Tg(Lck-cre)548Jxm/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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